Trial and cure-program status families can track.
Built from ClinicalTrials.gov status on programs we watch. Type1Cure never implies you are eligible — talk with your care team before any trial decision.
Programs with recruiting activity
From the live cure pipeline (8 programs tracked). Always verify on the registry page.
Recent trial feed items
C-Carbs: A CGM-guided Approach to Teaching Carb Awareness
RECRUITING, NA. Interventions: C-Carbs Program. Locations: Los Angeles, California, United States. The goal of this randomized study is to learn whether a CGM-guided insulin dosing education program can help adults with diabetes improve how they dose mealtime insulin. The main question it aims to answer is: 1\. Does CGM-guided insulin dosing education improve insulin dosing behaviors and glycemic outcomes in adults with diabetes who do not routinely use c...
Effectiveness of a Combined mHealth-CBT Psychological Intervention to Improve Psychological Well-Being in Young Patients With T1D
RECRUITING, NA. Interventions: Cognitive-Behavioral Therapy: face-to-face + app. Locations: Córdoba, Córdoba, Spain. Type 1 diabetes (T1D) can lead to psychological adjustments that impact the acceptance and management of this health condition, as well as the overall quality of life of patients, especially among the young. Therefore, there is a need for psychological interventions aimed at enhancing the psychological well-being of children and adolescents...
The Gut Microbiome in Type 1 Diabetes and Mechanism of Metformin Action
RECRUITING, PHASE2. Interventions: Metformin. Locations: Indianapolis, Indiana, United States. Ovwerweight and obesity prevalence in persons with T1D has increased, which further complicates management and risk for complications. The proposed study is relevant to public health because it helps us understand the role of the gut microbiome in disease pathophysiology in T1D youth with overweight and obesity as well as potential mechanisms to modify disease.
Circadian Mechanisms, Glucose, and CV Risks in T1D
RECRUITING, NA. Interventions: Sleep stability intervention. Locations: Chicago, Illinois, United States. People with type 1 diabetes are disproportionately affected by cardiovascular disease (CVD). Short and irregular sleep have been associated with cardiovascular risk in this population. Improving sleep regularity has been associated with improved glycemic markers however mechanisms by which improving sleep regularity improves metabolic and cardiovascul...
Pediatric Insulin Plan Calculator for T1DM Management
RECRUITING, NA. Interventions: Flexible Digital Insulin Dose Calculator. Locations: Mosul, Iraq | Lahore, Pakistan. This is a multi-centre, prospective, randomized, open-label controlled trial designed to evaluate the effectiveness of a flexible digital insulin dose calculator in children under 12 years of age with Type 1 Diabetes Mellitus (T1DM) managed with multiple daily injections (MDI). Participants will be stratified by continuous glucose monitoring...
Type 1 Diabetes REst for Metabolic Health
RECRUITING, NA. Interventions: Sleep Health and Circadian Timing Intervention. Locations: Aurora, Colorado, United States. Research has shown a link between poor sleep health and late circadian timing with cardiometabolic health in adolescents with type 1 diabetes (T1D). Cardiovascular disease (CVD) is the leading cause of morbidity and mortality in T1D, which begins as early as adolescence, and current therapies are limited. Therefore, this study plans t...
Health Behavior Intervention for Adults With Type 1 Diabetes
RECRUITING, NA. Interventions: CB Sleep. Locations: Atlanta, Georgia, United States. Type 1 diabetes (T1D) affects approximately 2 million Americans, and only 2 in 8 young adults ages 18-31 years achieve glycemic targets (glycated hemoglobin A1C \<7.0%). Achieving glycemic targets is associated with reduced risk of micro-and macrovascular complications. Sleep deprivation leads to impaired glucose tolerance and insulin sensitivity in adults without chronic...
Optimising the Delivery of Diabetes Distress Informed Care for Its Prevention, Detection, and Management in Adults With Type 1 Diabetes: a Feasibility Study (D-stress Study)
RECRUITING, NA. Interventions: D-stress study: The detection, prevention and management of diabetes distress for adults living with type 1 diabetes.. Locations: Bath, United Kingdom | Leicester, United Kingdom | London, United Kingdom. Up to one in two adults with type 1 diabetes find living with and managing diabetes to be emotionally challenging. This 'emotional side' of diabetes - feeling worried, frustrated, overwhelmed, sad, burnt-out - is called dia...
Also on the tracker
- VX-264 (encapsulated islet cells)Early clinical trial
- Hypoimmune islet cells (UP421 / SC451)First-in-human / early research
- Cell Pouch islet transplantClinical trial
- Tegoprubart (immune protection)Clinical trial
- Teplizumab (Tzield)FDA approved (delays onset)
- KRIYA-839 gene therapyPreclinical
- Gene-edited cell replacementEarly research
These are research programs pursuing a functional cure or disease modification for type 1 diabetes. None is a confirmed, broadly available cure. Trial status is informational, not medical advice, and not a recruiting offer. Verify eligibility and details with the official trial record and a clinician.